January 29, 2012
What Are the Pulmonary Embolism Risk Factors for Children?
What Are the Pulmonary Embolism Risk Factors
for Children?
< / TD>
children is valid and risk factors for pulmonary embolism?
Children Suspected of Having Pulmonary
Embolism: Multidetector CT Pulmonary Angiography – Thromboembolic
Risk Factors and Implications for Appropriate Use < br />
risk factors for thrombosis and signs to guide children with suspected pulmonary embolism multi CT pulmonary angiography
Lee EY, Tse SK, Zurakowski D, et al
Lee EY, Tse SK, Zurakowski D, et al < br />
Radiology. 2012; 262:242-251
Radiology. 2012; 262:242-251
Summary
Summary
< / TD>
The goal of this study was to assess the thromboembolic risk
factors that may be associated with positive detection of pulmonary
embolism (PE) on computed tomographic pulmonary angiography (CTPA).
The cohort included 227 pediatric patients who underwent CTPA for < br /> suspected PE. Age, referral setting (inpatient, outpatient,
emergency department), clinical signs and symptoms, d-dimer result,
type of multidetector CT scanner (16 -, 32 -, 64 -detector row), and
several risk factors (immobilization, indwelling central venous
catheter, prior PE and / or deep venous thrombosis, hypercoagulable
state, excess estrogen state, malignancy, cardiac disease) were
compared in patients with and without PE, using multiple logistic
regression modeling. CTPA was positive for PE in 16% of patients.
Five statistically significant risk factors for PE on CTPA were
identified, including immobilization, hypercoagulable state, excess
estrogen state, indwelling central venous line, and prior PE and / or
deep venous thrombosis. When 2 or more of these risk factors were
used to define a clinical threshold for performing CTPA, the
sensitivity and specificity for detection of PE were 89% and 94%,
respectively.
purpose of this study is to assess risk factors for thrombosis by CT pulmonary angiography (CTPA) confirmed the relevance of pulmonary embolism. Study included 227 children with suspected pulmonary embolism, and for CT pulmonary angiography. Children divided into groups with or without pulmonary embolism, more age, source of patients (inpatient, outpatient, emergency), clinical symptoms and signs, D-dimer results, CT types (16,32,64 row) and other risk factors ( constraints fixed, central venous catheter, previous pulmonary embolism and / or deep vein thrombosis, hypercoagulable state, high estrogen levels, cancer, heart disease), through the Logistic regression analysis modeling. 16% of children with confirmed pulmonary embolism by CTPA. The study found that with confirmed pulmonary embolism by CTPA has five statistically significant risk factors, including: constraints fixed, hypercoagulable state, high estrogen levels, the central venous catheter, previous pulmonary embolism and / or deep vein thrombosis. Two or more than 2 risk factors can propose that CTPA examination, pulmonary embolism detected at this time the sensitivity and specificity were 89% and 94%.
Viewpoint
view
PE is a serious clinical condition that requires accurate early
diagnosis and appropriate treatment. The incidence of PE in the
pediatric population ranges from 0.73% to 4.2%. [1]
CTPA has been demonstrated to be useful in direct visualization of
PE in adult patients with sensitivity of 83% -100% and specificity
of 89% -97%. [2]
With the current increasing emphasis on appropriate utilization of
imaging and reduction of radiation exposure, this study in a
pediatric population is timely and clinically relevant. The
investigators concluded that it is very unlikely for CTPA to be
positive for PE in children with no thromboembolic risk factors
(0.5% with 95% confidence interval , 0.1% -2%). In fact, they suggest
that ventilation / perfusion (V / Q) scanning in children older than 5
years (who can follow the breathing instruction) may be considered, < br /> as the likelihood of a diagnostic quality V / Q scan is high, in view
of the expected lower probability of underlying lung disease in the
pediatric population in comparison with that in adults. Another
interesting observation in this investigation was that d-dimer
testing added little unique value in identifying patients with PE.
However, as the investigators note, this may reflect the order of
the tests and the clinician decision-making process.
pulmonary embolism is a serious clinical disease and requires early diagnosis and proper treatment. The incidence of pulmonary embolism in children, 0.73% to 4.2% [1]. CTPA has been shown in adults is very effective visual display of pulmonary embolism, 83% -100% sensitivity and specificity of 89% -97% [2]. With the current imaging techniques to improve and reduce radiation exposure to the growing importance of this study is essential for the children concerned, but also great clinical value. The researchers concluded: If the children do not present risk factors for thrombosis, the CTPA is almost non-existent confirm pulmonary embolism. (95% confidence interval: 0.1% -2%). In fact, the researchers suggest, if children with more than 5 years old (you can follow the instructions to breathe), you can choose the expiratory / inspiratory (V / Q) scan. Because the current view is that, compared with adults, children, low incidence of lung disease, the V / Q scan diagnosis is relatively high. Another interesting finding is that, D-dimer with or without pulmonary embolism in identifying meaningful. However, the researchers also pointed out that the phenomenon may be related to test time or test itself.
1.
Buck JR, Connors RH, Coon WW, Weintraub WH, Wesley JR, Coran AG.
Pulmonary embolism in children. J Pediatr Surg.
1981; 16:385-391.
2. < br /> Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed
tomography for acute pulmonary embolism. N Engl J Med.
2006; 354:2317-2327.
January 3, 2012
Fubon Media Technology Co., Ltd. (Fubon Multimedia Technology Co., Ltd.)
December 23, 2011
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[Switch] EFFECT OF A COMPUTER-BASED MULTIMEDIA
EFFECT OF A COMPUTER-BASED
MULTIMEDIA
EDUCATIONAL MODULE ON KNOWLEDGE OF THE MENSTRUAL CYCLE
Joan L. Moon EM>
A Dissertation
EM>
Submitted to the Graduate College of Bowling Green
State University in partial fulfillment of
the requirements of the degree of
DOCTOR OF EDUCATION
CHAPTER I.
INTRODUCTION
STRONG> Background of the Problem
The menstrual cycle is an intricate web of hormonal interactions in
the female body
impacting a woman fertility, health, and sense of wellbeing.
Supporting human reproduction is
a hallmark of the menstrual cycle. Fertility awareness is defined
as observing and interpreting
the signs resulting from the interplay of hormones in the menstrual
cycle, and applying the
information gained in self-awareness and reproductive healthcare
decision-making (Pyper,
1997).
While a small number of women utilize fertility awareness in order
to practice natural
family planning, an understanding of the menstrual cycle is
fundamental to all women
attentiveness to their reproductive health (Clubb, Pyper,